The best Side of nature of pharmaceutical APIs
The best Side of nature of pharmaceutical APIs
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Daunorubicin interacts with DNA by intercalation and inhibition of macromolecular biosynthesis. This inhibits the development in the enzyme topoisomerase II, which relaxes supercoils in DNA for transcription.
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Epirubicin is favoured in excess of doxorubicin, the preferred anthracycline, in certain chemotherapy regimens since it appears to bring about less side effects. In 1999 epirubicin been given FDA acceptance being a part of adjuvant therapy in node-good sufferers.